Stimerex Hardcore 25mg Ephedra 200mg PEA Alkaloids 90ct

Stimerex Hardcore by Hi Tech delivers the #1 selling hardcore ephedra diet pill that consists of 25mg ephedra and 200mg of phenylethylamine (PEA) alkaloids. Stimerex Hardcore is designed for those looking for serious weight loss and energy boost. The potent ephedra blend is legal in all 50 states. Stimerex Hardcore is easily recognizable with the black capsules. It has been used for decades for its high energy boost and metabolism stimulating properties.

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200mg PEA Alkaloids

Hi Tech has found the answer to replicating the ephedra benefits from a couple decades ago. The answer is senegalia berlandieri extract which 200mg of PEA alkaloids are derived. PEA alkaloids have similar properties to ephedra alkaloids and now considered to be the best replacement on the market. Hi Tech claims that the PEA alkaloids have shown in research to increase metabolism greater than 30mg of ephedrine.

Research has demonstrated ephedrine alkaloids increasing energy expenditure. For example, one 30mg ephedrine dosage increased calorie burning 6% and a second 10mg dosage increase 10%. Since 2000, people have been searching for the best alternative. More over, many people want these metabolic boosting benefits. Senegalia berlandieri extract is part of the acacia rigidula herbal family. The active PEA alkaloids compounds offer the best metabolic rate and fat burning increase potential. The 200mg plus PEA alkaloid study found a 12% increase in energy expenditure which matched and exceed the ephedrine research. Important to note that caffeine was added to most metabolic boosting clinical trials. (1)

25mg Ephedra

Stimerex Hardcore was designed for the experienced diet pill consumer that wants intense energy fast and an energy boost that lasts. Stimerex Hardcore 25mg ephedra is one of the most cutting edge diet pill supplements on the market. The hardcore energy blend of Stimerex Hardcore consists of other successful weight loss herbs including theobromine, caffeine, green tea extract, and yohimbe.

Recent research investigates ephedra weight loss efficacy and safety. In other words, does ephedra work and is it safe. One review summarized leading clinical trials and research. The review searched ephedra and ephedrine results. Over 500 different papers analyzed. The conclusion ephedra delivers weight loss. The clinical trials were mostly short-term studies. Many of the studies included caffeine. Caffeine and ephedra dosages popular diet pill ingredients. (2)

Stimerex Hardcore Difference

What makes Stimerex Hardcore different than other ephedra diet pills? The key difference is the potent blend of PEA alkaloids combined with successful weight loss ingredients of ephedra, theobromine, caffeine, and more.

SUGGESTED USE: Take 1-2 tablets in the morning and 1 tablet after lunch. Do not exceed 4 tablets in a 24 hour period.

Clinical Trials and Research Studies

In recent years, the use of dietary supplements for weight loss and performance enhancement has gained significant popularity. One particular supplement that has attracted attention is Ephedra, a natural herb derived from the plant Ephedra sinica. Ephedra contains several active compounds, including ephedrine and pseudoephedrine, which have been found to have sympathomimetic and thermogenic effects. The potential benefits of Ephedra in promoting weight loss and increasing metabolism have led to numerous clinical trials and research studies.

This comprehensive review aims to provide an in-depth analysis of the efficacy and safety of Ephedra based on the available clinical trials and research. By examining the findings from various studies, we seek to present a balanced perspective on the use of Ephedra as a dietary supplement.

Historical Background of Ephedra

Ephedra has a long history of use in traditional Chinese medicine for its stimulating and bronchodilatory properties. It was first synthesized in Germany in 1887 by chemist Lazǎr Edeleanu, who named it phenylisopropylamine. In the early 20th century, pharmaceutical companies introduced ephedrine inhalers for the treatment of nasal congestion. Methamphetamine, a derivative of ephedrine, was synthesized later and gained popularity as a recreational drug. (4)

Clinical Trials on Ephedra

Several clinical trials have been conducted to evaluate the efficacy of Ephedra as a weight loss supplement. In a randomized, double-blinded study by Bent et al. (year), obese Korean premenopausal women were administered Ephedra extract in combination with a low-calorie diet for 8 weeks. The study found a significant reduction in body mass index (BMI) in the group that received Ephedra compared to the placebo group. However, no significant changes were observed in resting metabolic rate (RMR) among the groups. (8)

Another study by Phillips et al. (year) investigated the safety of Ephedra by analyzing the Toxic Event Surveillance System (TESS) reports. The study found that adverse events related to Ephedra were relatively low compared to its sales data, suggesting a favorable safety profile. However, it is important to note that these findings were based on reported adverse events and may not capture the full extent of potential risks associated with Ephedra use. (5)

Research on the Mechanism of Action

To understand the mechanism of action of Ephedra, researchers have focused on its active compounds, ephedrine, and pseudoephedrine. These compounds have been found to have sympathomimetic effects, stimulating the central nervous system and increasing heart rate and blood pressure. They also have thermogenic properties, increasing metabolic rate and energy expenditure.

One study by (author) investigated the distribution of beta-phenylethylamine (PE), a compound found in Ephedra, in rat brains. The study found that PE was evenly distributed throughout the various regions of the brain. Additionally, experiments with deuterated PE analogs suggested that the enrichment of deuterated PE compared to PE was due to protection from the actions of monoamine oxidase, leading to pronounced deuterium substitution effects in vivo. (6)

Safety Considerations and Adverse Effects

The safety of Ephedra has been a subject of debate and scrutiny due to reports of adverse events. Adverse effects associated with Ephedra use include increased heart rate, elevated blood pressure, nervousness, insomnia, and gastrointestinal disturbances. In rare cases, severe cardiovascular events, such as myocardial infarction and stroke, have been reported.

To address these concerns, regulatory bodies in various countries have imposed restrictions on the sale and use of Ephedra-containing products. The United States Food and Drug Administration (FDA) banned the sale of dietary supplements containing Ephedra alkaloids in 2004 due to safety concerns. However, it is important to note that these restrictions may vary across different jurisdictions.

Conclusion

In conclusion, Ephedra has been extensively studied in clinical trials and research to evaluate its efficacy and safety as a dietary supplement. The findings from these studies suggest that Ephedra may have potential benefits in promoting weight loss, but its effects on resting metabolic rate are inconclusive. Safety considerations should be taken into account, as Ephedra has been associated with adverse effects, particularly cardiovascular events. Regulatory restrictions on the sale and use of Ephedra-containing products further highlight the need for caution when considering its use.

It is important for individuals to consult with healthcare professionals before starting any dietary supplement regimen, including Ephedra. Further research is needed to fully understand the long-term effects and potential risks associated with Ephedra use.

Supplement Facts

Servings Size: 1 capsule

Servings Per Container: 90

Proprietary Blend: 475mg

Ephedra extract 25mg (leaves), senegalia berlandieri extract (leaves) {yielding 200mg phenylethylamine alkaloids including: methylsynephrine, n-methyl-b-phenylethylamine, n, n-dimethylphenylethylamine, phenylethylamine}, 2-aminoisoheptane hcl, theobromine, green tea extract (leaves), naringen (fruit), 3-dimethyl aminoethanol bitartrate, yohimbe extract (bark)

Caffeine (anhydrous) 150mg

The statements on this page have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Before beginning any program of weight loss, consult your health care practitioner.